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[Solved]: A 40-year-old African American man is seen in the…

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A 40-year-old African American man is seen in the emergency room for a severe headache. His blood pressure is 180/110 mm Hg, and he has evidence of retinal hemorrhage. An infusion of nitroprusside is given. When nitroprusside is given in higher than usual doses (produces traces of cyanide toxicty), it may be accompanied by the administration of thiosulfate to reduce potential toxic side effects. Which complex associated with electron transport or oxidative phosphorylation is most sensitive to the toxic byproduct that may accumulate with high doses of nitroprusside?

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