[Answered]: A steady-state plasma concentration of 20 mg/L…

A steady-state plasma concentration of 20 mg/L was measured when a drug was given by IV infusion to healthy volunteers (average weight, 75 kg) at a rate of 5.5 mg/kg/hr for 6 hours. (a) Calculate the total body clearance for this drug. (b) When the IV infusion was discontinued, plasma drug concentration decreased exponentially, declining to 2.5 mg/L at 8.5 hours after the start of the infusion. Calculate the volume of distribution (VD)