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[Expert Solution]: Case #4 Patient Information Three units of…

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Case #4 Patient Information Three units of RBCs were ordered for a 56-year-old woman scheduled for a thoracotomy. Results of pre-surgical compatibility testing were as follows: Serological Testing Serological Testing Anti-A Anti-B Anti-D A1 Cells B Cells 3+ 0 3+ 2+ 4+ IS 37C/LISS AHG CC SCI NT 0 0 2+ SCII NT 0 0 2+ SCIII NT 0 0 2+ Unit 1, A Pos 2+ 0 0 2+ Unit 2, A Pos 1+ 0 0 2+ Unit 3, A Pos 0 0 0 2+ Questions: 1. Is the ABO discrepancy in the patient forward type or reverse type testing? Additional Testing: Because the crossmatch was incompatible at the immediate spin phase, an immediate spin panel was performed. Anti-P1 was identified. Questions: 2. Is it likely that the causes of the ABO discrepancy and incompatible crossmatch are the same? Why or why not? 3. What additional testing should be performed to resolve the ABO discrepancy?

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