Mr. H. was diagnosed with atrial fibrillation six years ago and was prescribed Warfarin, an anticoagulant drug that reduces the risk of developing a blood clot. Besides his anticoagulant medication, Mr. H. was on medication for gastroesophageal reflux disease (GERD). Mr. H. knew that he could not eat green leafy vegetables and broccoli because these foods interfered with his medication, so he avoided these foods. Mr. H. began to demonstrate signs of a urinary tract infection. To try and keep it from getting worse he started drinking 12 oz. of cranberry juice a day. A week after Mr. H. started drinking cranberry juice, he was admitted to hospital for significant hematuria and sepsis. Mr. H.’s admitting physician stated that the cranberry juice was a P450 enzyme inducer and increased the serum levels of warfarin leading to hemorrhage. Answer the following: Discuss how foods and supplements can interact with certain medications. Describe why the LPN needs to be aware of food-drug adverse reactions?
[Expert Solution]: Mr
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