[Expert Solution]: The nurse is reviewing medication…

The nurse is reviewing medication information with a nursing student prior to administering an oral drug and notes that the drug has extensive first-pass effects. Which statement by the student indicates an understanding of the first-ass effect? “The first-pass effect means the drug was given by injection and immediately metabolized.” “The first-pass effect means the drug may be unchanged as it passes through the liver.” “The first-pass effect means the drug is absorbed from the GI tract into the portal vein where it is transported to the liver and metabolized.” “The first-pass effect means the drug has 100% bioavailability.”