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[Expert Solution]: 58-year-old man with a history of chronic…

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58-year-old man with a history of chronic hepatitis C presents with fatigue and abdominal distention. Physical examination reveals splenomegaly and visible abdominal veins. Laboratory studies show thrombocytopenia, and an upper endoscopy confirms esophageal varices. These findings are most consistent with which underlying pathophysiologic process?

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