[Expert Solution]: A 55-year-old woman with hand…

A 55-year-old woman with hand osteoarthritis asks about joint supplements. She has read about glucosamine and chondroitin and wants to know if they will help. Her pain is moderate (5/10) and she has Heberden’s nodes on multiple DIPs. What is the MOST evidence-based response? Question 22Select one: a. “Evidence is mixed and they likely provide minimal to no benefit, but they are generally safe if you want to try them” b. “These supplements have strong evidence for benefit and I recommend trying them for 3 months” c. “These work better than NSAIDs and should be your first-line treatment” d. “These supplements are dangerous and have significant side effects, so I don’t recommend them”